The Notch pathway stabilizes sprouting angiogenesis by favoring stalk cells over tip cells at the vascular front. Because tip and stalk cells have different properties in morphology and function, ...

The Notch signalling pathway is one of the few fundamental signalling pathways that govern metazoan development. Notch signals couple cell fate acquisition by an individual cell to the cell fate ...

The Notch signaling cascade is deregulated by oncogenic lesions in human cancers and has therefore become an attractive therapeutic target. Inhibitory monoclonal antibodies and small-molecule ...

Notch proteins regulate a broad spectrum of cell fate decisions and differentiation processes during fetal and postnatal development. Mammals have four Notch receptors that bind five different ligands ...

Fascinated by the developments taking place in the consumer technology industry, Shikhar Mehrotra has been putting his thoughts and ideas into words for the last four years. He is based out of India, ...

Truly pattern: Nonlinear integration of motion signals is required to account for the responses of pattern cells in rat visual cortex In the mammalian brain, Notch signaling maintains the cortical ...